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Many drugs can interact with ticagrelor. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any you start or stop using, especially:

• imatinib;

• lovastatin (Advicor, Altoprev, Mevacor) or simvastatin (Zocor, Simcor, Vytorin, Juvisync);

• nefazodone;

• St. John's wort;

• an antibiotic--clarithromycin, telithromycin;

• antifungal medicine--itraconazole, ketoconazole, posaconazole, voriconazole;

• heart or blood pressure medicine--digoxin, nicardipine, quinidine;

• antiviral medicine to treat hepatitis or HIV/AIDS--atazanavir, boceprevir, cobicistat, delavirdine, efavirenz, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir, telaprevir;

• seizure medicine--carbamazepine, phenytoin; or

• tuberculosis medicine--isoniazid, rifampin.

This list is not complete and many other drugs can interact with ticagrelor. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

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